Part of the Paphos to Limassol road near Pissouri will remain closed during the weekend police said, due to rock slides.
Crews from the public works department are working to restore the problem and the work is expected to completed by Monday, police said.
During works, part of the motorway near the Pissouri exit up to the Avdimou exit will remain closed throughout the weekend.
Traffic will be channelled through the Pissouri exit to the old Paphos to Limassol road.
Motorists are urged to be alert, drive at low speed, keep a safe distance from other vehicles, and abide by traffic signs.