The Nicosia municipal council has voted to keep Costakis Pantelides street, which links Eleftheria square with Solomou square, free of cars, it announced on Friday.
The decision to pedestrianise the road was taken after a consultation with organised groups, the municipality said.
The street has been closed to cars for more than a year while development works in Eleftheria Square have been carried out.
Opinions on the opening of the road to cars have been divided.
The Nicosia Pedestrian Association in March asked people to back them.
They organised a protest outside the multipurpose centre in Pallouriotissa at the time, where residents asked for the road to remain car free.
The residents sent a letter to Mayor Constantinos Yiorkadjis accompanied by 3,000 signatures, saying that allowing the circulation of cars on Costakis Pantelides street would severely affect the quality of life of the capital’s residents.
Another association which represents 100 shopkeepers in the centre of Nicosia called for cars to be banned from the parallel Rigainis street as a priority over pedestrianising Costakis Pantelides street.
The association said it does not disagree with turning Costakis Pantelides street into a pedestrian zone but argues that Rigainis street should be developed with proper lighting and without cars parked along the road first.
They also believe other pedestrian areas in the vicinity will be supported this way.