U.S. actress Anne Heche, 53, died after her life support was turned off, a week after her fiery car crash in Los Angeles, the Daily Mail reported on Friday.

The Hollywood actress was in critical condition, comatose and connected to a breathing machine after suffering severe injuries in a fiery Los Angeles car crash, a spokesperson for the performer said.

Heche, 53, had been hospitalized since shortly after the compact car she was driving sped out of control in a Westside neighborhood of Los Angeles late Friday morning, plowed into a house and burst into flames, according to police.

No one inside the home was hurt, but the impact set the dwelling ablaze, requiring a response by dozens of firefighters.

Heche came to prominence for her Emmy-winning work on the daytime television drama “Another World” and went on to star in other screen roles including the HBO series “Hung” and such films as “Wag the Dog” and “Cedar Rapids.”

She made tabloid headlines in the late 1990s for an affair with comedian Ellen DeGeneres around the time that DeGeneres came out publicly as a lesbian. Following their split, Heche wed cameraman Coleman Laffoon, but they later divorced, and she spent some years after that in a relationship with actor James Tupper, her co-star in the short-lived TV show “Men in Trees.”